Artigos Científicos

23/12/2016 - Genetic analyses of Per.C6 cell clones producing a therapeutic monoclonal antibody regarding productivity and long-term stability.

Tsuruta LR, Lopes Dos Santos M, Yeda FP, Okamoto OK, Moro AM. Appl Microbiol Biotechnol. 2016 Dec;100(23):10031-10041. Epub 2016 Sep 27.

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06/11/2016 - The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor.

Girola N, Matsuo AL, Figueiredo CR, Massaoka MH, Farias CF, Arruda DC, Azevedo RA, Monteiro HP, Resende-Lara PT, Cunha RL, Polonelli L, Travassos LR. Peptides. 2016 Nov; 85:1-15. doi: 10.1016/j.peptides.2016.08.006. Epub 2016 Aug 26.

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01/08/2015 - A phase II trial with anti-Lewis-Y monoclonal antibody (hu3S193) for the treatment of platinum resistant / refractory ovarian, fallopian tube and primary peritoneal carcinoma.

Smaletz O, Diz MD, do Carmo CC, Sabbaga J, Cunha-Junior GF, Azevedo SJ, Maluf FC, Barrios CH, Costa RL, Fontana AG, Madrigal V, Wainstein AJ, Yeda FP, Alves VA, Moro AM, Blasbalg R, Scott AM, Hoffman EW. Gynecol Oncol. 2015 Aug;138(2):272-7. doi: 10.1016/j.ygyno.2015.05.023.

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13/05/2015 - Binding Affinity, Specificity and Comparative Biodistribution of the Parental Murine Monoclonal Antibody MX35 (Anti-NaPi2b) and Its Humanized Version Rebmab200.

Lindegren S, Andrade LN, Bäck T, Machado CM, Horta BB, Buchpiguel C, Moro AM, Okamoto OK, Jacobsson L, Cederkrantz E, Washiyama K, Aneheim E, Palm S, Jensen H, Tuma MC, Chammas R, Hultborn R, Albertsson P. PLoS One. 2015 May 13;10(5): e0126298. doi: 10.1371/journal.pone.0126298. eCollection 2015.

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31/07/2013 - Rebmab200, a Humanized Monoclonal Antibody Targeting the Sodium Phosphate Transporter NaPi2b Displays Strong Immune Mediated Cytotoxicity against Cancer: A Novel Reagent for Targeted Antibody Therapy of Cancer.

Dos Santos ML, Yeda FP, Tsuruta LR, Horta BB, Pimenta AA Jr, Degaki TL, Soares IC, Tuma MC, Okamoto OK, Alves VA, Old LJ, Ritter G, Moro AM. PLoS One. 2013 Jul 31,8(7): e70332. doi: 10.1371/journal.pone.0070332.

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